2z4b: Difference between revisions

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[[Image:2z4b.jpg|left|200px]]<br /><applet load="2z4b" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2z4b.jpg|left|200px]]
caption="2z4b, resolution 2.34&Aring;" />
 
'''Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand'''<br />
{{Structure
|PDB= 2z4b |SIZE=350|CAPTION= <scene name='initialview01'>2z4b</scene>, resolution 2.34&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DC8:(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL'>DC8</scene>
|ACTIVITY=
|GENE= ESR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Z4B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DC8:'>DC8</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z4B OCA].  
2Z4B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z4B OCA].  


==Reference==
==Reference==
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification., Richardson TI, Dodge JA, Durst GL, Pfeifer LA, Shah J, Wang Y, Durbin JD, Krishnan V, Norman BH, Bioorg Med Chem Lett. 2007 Sep 1;17(17):4824-8. Epub 2007 Jun 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17614275 17614275]
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification., Richardson TI, Dodge JA, Durst GL, Pfeifer LA, Shah J, Wang Y, Durbin JD, Krishnan V, Norman BH, Bioorg Med Chem Lett. 2007 Sep 1;17(17):4824-8. Epub 2007 Jun 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17614275 17614275]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transcription]]
[[Category: transcription]]


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