2z60: Difference between revisions

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[[Image:2z60.gif|left|200px]]<br /><applet load="2z60" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2z60.gif|left|200px]]
caption="2z60, resolution 1.95&Aring;" />
 
'''Crystal Structure of the T315I Mutant of Abl kinase bound with PPY-A'''<br />
{{Structure
|PDB= 2z60 |SIZE=350|CAPTION= <scene name='initialview01'>2z60</scene>, resolution 1.95&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=P3Y:5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE'>P3Y</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2]
|GENE=
}}
 
'''Crystal Structure of the T315I Mutant of Abl kinase bound with PPY-A'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Z60 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=P3Y:'>P3Y</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z60 OCA].  
2Z60 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z60 OCA].  


==Reference==
==Reference==
Crystal structure of the T315I mutant of AbI kinase., Zhou T, Parillon L, Li F, Wang Y, Keats J, Lamore S, Xu Q, Shakespeare W, Dalgarno D, Zhu X, Chem Biol Drug Des. 2007 Sep;70(3):171-81. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17718712 17718712]
Crystal structure of the T315I mutant of AbI kinase., Zhou T, Parillon L, Li F, Wang Y, Keats J, Lamore S, Xu Q, Shakespeare W, Dalgarno D, Zhu X, Chem Biol Drug Des. 2007 Sep;70(3):171-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17718712 17718712]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: transferase]]
[[Category: transferase]]


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