2z6u: Difference between revisions

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[[Image:2z6u.gif|left|200px]]<br /><applet load="2z6u" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2z6u.gif|left|200px]]
caption="2z6u, resolution 2.72&Aring;" />
 
'''Ternary structure of the Glu119Ala M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy'''<br />
{{Structure
|PDB= 2z6u |SIZE=350|CAPTION= <scene name='initialview01'>2z6u</scene>, resolution 2.72&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37]
|GENE= hhaIM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=735 Haemophilus parahaemolyticus])
}}
 
'''Ternary structure of the Glu119Ala M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Z6U is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_parahaemolyticus Haemophilus parahaemolyticus] with <scene name='pdbligand=SAH:'>SAH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6U OCA].  
2Z6U is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_parahaemolyticus Haemophilus parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z6U OCA].  


==Reference==
==Reference==
AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI., Shieh FK, Reich NO, J Mol Biol. 2007 Nov 9;373(5):1157-68. Epub 2007 Aug 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17897676 17897676]
AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI., Shieh FK, Reich NO, J Mol Biol. 2007 Nov 9;373(5):1157-68. Epub 2007 Aug 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17897676 17897676]
[[Category: DNA (cytosine-5-)-methyltransferase]]
[[Category: DNA (cytosine-5-)-methyltransferase]]
[[Category: Haemophilus parahaemolyticus]]
[[Category: Haemophilus parahaemolyticus]]
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[[Category: transferase/dna complex]]
[[Category: transferase/dna complex]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:00:35 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:52:42 2008''