4clb: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "4clb" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
''' | ==N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH IBET-295== | ||
<StructureSection load='4clb' size='340' side='right' caption='[[4clb]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4clb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CLB FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=83T:PROPAN-2-YL+N-[(2S,4R)-1-ETHANOYL-2-METHYL-6-[4-(METHYLAMINOMETHYL)PHENYL]-3,4-DIHYDRO-2H-QUINOLIN-4-YL]CARBAMATE'>83T</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cl9|4cl9]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4clb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4clb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4clb RCSB], [http://www.ebi.ac.uk/pdbsum/4clb PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Atkinson, S]] | |||
[[Category: Chung, C]] | |||
[[Category: Transcription]] | |||
Revision as of 11:04, 24 December 2014
N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH IBET-295
| ||||||||||||
