4o61: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4o61|  PDB=4o61  |  SCENE=  }}
===Structure of human ALKBH5 crystallized in the presence of citrate===


The entry 4o61 is ON HOLD until Feb 22 2015
==Function==
[[http://www.uniprot.org/uniprot/ALKB5_HUMAN ALKB5_HUMAN]] Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m(6)A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m(6)A mRNA affects mRNA processing and export and is required for spermatogenesis.<ref>PMID:21264265</ref> <ref>PMID:23177736</ref>  


Authors: Tempel, W., Chao, X., Liu, K., Dong, A., Cerovina, T., He, H., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
==About this Structure==
[[4o61]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O61 OCA].  


Description: Structure of human ALKBH5 crystallized in the presence of citrate
==Reference==
<references group="xtra"/><references/>
[[Category: Arrowsmith, C H.]]
[[Category: Bountra, C.]]
[[Category: Cerovina, T.]]
[[Category: Chao, X.]]
[[Category: Dong, A.]]
[[Category: Edwards, A M.]]
[[Category: He, H.]]
[[Category: Liu, K.]]
[[Category: Min, J.]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Tempel, W.]]
[[Category: Dioxygenase]]
[[Category: Oxidoreductase]]
[[Category: Rna demethylase]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/4o61"