3zif: Difference between revisions
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{{Large structure}} | |||
{{STRUCTURE_3zif| PDB=3zif | SCENE= }} | {{STRUCTURE_3zif| PDB=3zif | SCENE= }} | ||
===Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly=== | ===Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly=== | ||
{{ABSTRACT_PUBMED_24503080}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA]. | [[3zif]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovine_adenovirus_3 Bovine adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZIF OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:024503080</ref><references group="xtra"/><references/> | |||
[[Category: Bovine adenovirus 3]] | [[Category: Bovine adenovirus 3]] | ||
[[Category: Cheng, L.]] | [[Category: Cheng, L.]] | ||
Revision as of 15:15, 19 February 2014
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Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly
Template:ABSTRACT PUBMED 24503080
Function
[CAPSH_ADEB3] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus (By similarity).
About this Structure
3zif is a 18 chain structure with sequence from Bovine adenovirus 3. Full crystallographic information is available from OCA.
Reference
- Cheng L, Huang X, Li X, Xiong W, Sun W, Yang C, Zhang K, Wang Y, Liu H, Huang X, Ji G, Sun F, Zheng C, Zhu P. Cryo-EM structures of two bovine adenovirus type 3 intermediates. Virology. 2014 Feb;450-451:174-81. doi: 10.1016/j.virol.2013.12.012. Epub 2014, Jan 3. PMID:24503080 doi:https://dx.doi.org/10.1016/j.virol.2013.12.012