2zgd: Difference between revisions

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[[Image:2zgd.jpg|left|200px]]<br /><applet load="2zgd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2zgd.jpg|left|200px]]
caption="2zgd, resolution 1.900&Aring;" />
 
'''Asn-hydroxylation stabilises the ankyrin repeat domain fold'''<br />
{{Structure
|PDB= 2zgd |SIZE=350|CAPTION= <scene name='initialview01'>2zgd</scene>, resolution 1.900&Aring;
|SITE= <scene name='pdbsite=AC1:Cd+Binding+Site+For+Residue+A+410'>AC1</scene>, <scene name='pdbsite=AC2:Cd+Binding+Site+For+Residue+A+411'>AC2</scene>, <scene name='pdbsite=AC3:Cd+Binding+Site+For+Residue+A+412'>AC3</scene>, <scene name='pdbsite=AC4:Cd+Binding+Site+For+Residue+A+413'>AC4</scene>, <scene name='pdbsite=AC5:Cd+Binding+Site+For+Residue+A+414'>AC5</scene>, <scene name='pdbsite=AC6:Cl+Binding+Site+For+Residue+A+415'>AC6</scene> and <scene name='pdbsite=AC7:Cl+Binding+Site+For+Residue+A+416'>AC7</scene>
|LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>
|ACTIVITY=
|GENE=
}}
 
'''Asn-hydroxylation stabilises the ankyrin repeat domain fold'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ZGD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=CD:'>CD</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Cd+Binding+Site+For+Residue+A+410'>AC1</scene>, <scene name='pdbsite=AC2:Cd+Binding+Site+For+Residue+A+411'>AC2</scene>, <scene name='pdbsite=AC3:Cd+Binding+Site+For+Residue+A+412'>AC3</scene>, <scene name='pdbsite=AC4:Cd+Binding+Site+For+Residue+A+413'>AC4</scene>, <scene name='pdbsite=AC5:Cd+Binding+Site+For+Residue+A+414'>AC5</scene>, <scene name='pdbsite=AC6:Cl+Binding+Site+For+Residue+A+415'>AC6</scene> and <scene name='pdbsite=AC7:Cl+Binding+Site+For+Residue+A+416'>AC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZGD OCA].  
2ZGD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZGD OCA].  


==Reference==
==Reference==
Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor., Coleman ML, McDonough MA, Hewitson KS, Coles C, Mecinovic J, Edelmann M, Cook KM, Cockman ME, Lancaster DE, Kessler BM, Oldham NJ, Ratcliffe PJ, Schofield CJ, J Biol Chem. 2007 Aug 17;282(33):24027-38. Epub 2007 Jun 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17573339 17573339]
Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor., Coleman ML, McDonough MA, Hewitson KS, Coles C, Mecinovic J, Edelmann M, Cook KM, Cockman ME, Lancaster DE, Kessler BM, Oldham NJ, Ratcliffe PJ, Schofield CJ, J Biol Chem. 2007 Aug 17;282(33):24027-38. Epub 2007 Jun 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17573339 17573339]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: McDonough, M A.]]
[[Category: McDonough, M A.]]
Line 20: Line 29:
[[Category: hydroxylated]]
[[Category: hydroxylated]]


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