3b2z: Difference between revisions

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[[Image:3b2z.jpg|left|200px]]<br /><applet load="3b2z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3b2z.jpg|left|200px]]
caption="3b2z, resolution 2.800&Aring;" />
 
'''Crystal Structure of ADAMTS4 (apo form)'''<br />
{{Structure
|PDB= 3b2z |SIZE=350|CAPTION= <scene name='initialview01'>3b2z</scene>, resolution 2.800&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/ADAMTS-4_endopeptidase ADAMTS-4 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.82 3.4.24.82]
|GENE= ADAMTS4, KIAA0688 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of ADAMTS4 (apo form)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3B2Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/ADAMTS-4_endopeptidase ADAMTS-4 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.82 3.4.24.82] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2Z OCA].  
3B2Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B2Z OCA].  


==Reference==
==Reference==
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5., Mosyak L, Georgiadis K, Shane T, Svenson K, Hebert T, McDonagh T, Mackie S, Olland S, Lin L, Zhong X, Kriz R, Reifenberg EL, Collins-Racie LA, Corcoran C, Freeman B, Zollner R, Marvell T, Vera M, Sum PE, Lavallie ER, Stahl M, Somers W, Protein Sci. 2008 Jan;17(1):16-21. Epub 2007 Nov 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18042673 18042673]
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5., Mosyak L, Georgiadis K, Shane T, Svenson K, Hebert T, McDonagh T, Mackie S, Olland S, Lin L, Zhong X, Kriz R, Reifenberg EL, Collins-Racie LA, Corcoran C, Freeman B, Zollner R, Marvell T, Vera M, Sum PE, Lavallie ER, Stahl M, Somers W, Protein Sci. 2008 Jan;17(1):16-21. Epub 2007 Nov 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18042673 18042673]
[[Category: ADAMTS-4 endopeptidase]]
[[Category: ADAMTS-4 endopeptidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: ZN]]
[[Category: ZN]]
[[Category: aggrecanase]]
[[Category: aggrecanase]]
[[Category: cleavage on pair of basic residues]]
[[Category: cleavage on pair of basic residue]]
[[Category: extracellular matrix]]
[[Category: extracellular matrix]]
[[Category: glycoprotein]]
[[Category: glycoprotein]]
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[[Category: zymogen]]
[[Category: zymogen]]


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