4l3o: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4l3o|  PDB=4l3o  |  SCENE=  }}
+===Crystal Structure of SIRT2 in complex with the macrocyclic peptide S2iL5===
+{{ABSTRACT_PUBMED_24389023}}
-The entry 4l3o is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/SIR2_HUMAN SIR2_HUMAN]] NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and non-histone proteins. Deacetylates 'Lys-40' of alpha-tubulin. Involved in the control of mitotic exit in the cell cycle, probably via its role in the regulation of cytoskeleton. Deacetylates PCK1, opposing proteasomal degradation. Deacetylates 'Lys-310' of RELA.<ref>PMID:12620231</ref> <ref>PMID:12697818</ref> <ref>PMID:21081649</ref> <ref>PMID:21726808</ref>
-Authors: Yamagata, K., Nishimasu, H., Ishitani, R., Nureki, O.
+==About this Structure==
+[[4l3o]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L3O OCA].
-Description: Human protein
+==Reference==
+<ref group="xtra">PMID:024389023</ref><references group="xtra"/><references/>
+[[Category: Ishitani, R.]]
+[[Category: Nishimasu, H.]]
+[[Category: Nureki, O.]]
+[[Category: Yamagata, K.]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Macrocyclic peptide]]
+[[Category: Structural change]]

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