3bgq: Difference between revisions

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[[Image:3bgq.gif|left|200px]]<br /><applet load="3bgq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3bgq.gif|left|200px]]
caption="3bgq, resolution 2.000&Aring;" />
 
'''Human Pim-1 kinase in complex with an triazolo pyridazine inhibitor VX2'''<br />
{{Structure
|PDB= 3bgq |SIZE=350|CAPTION= <scene name='initialview01'>3bgq</scene>, resolution 2.000&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=VX2:N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine'>VX2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human Pim-1 kinase in complex with an triazolo pyridazine inhibitor VX2'''
 


==About this Structure==
==About this Structure==
3BGQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=VX2:'>VX2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGQ OCA].  
3BGQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BGQ OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
Line 24: Line 33:
[[Category: transferase]]
[[Category: transferase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:05:32 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:58:46 2008''

Revision as of 16:58, 20 March 2008

File:3bgq.gif


Drag the structure with the mouse to rotate
3bgq, resolution 2.000Å
Ligands: VX2
Gene: PIM1 (Homo sapiens)
Activity: Non-specific serine/threonine protein kinase, with EC number 2.7.11.1
Coordinates: save as pdb, mmCIF, xml



Human Pim-1 kinase in complex with an triazolo pyridazine inhibitor VX2


About this Structure

3BGQ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 18:58:46 2008

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