4okh: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of calpain-3 penta-EF-hand domain==

~~The entry~~ 4okh is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4okh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKH OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OKH FirstGlance].

~~Authors~~: ~~Karunan Partha~~, S., ~~Ravulapalli~~, R., ~~Campbell, R~~.L., Allingham, J.S., Davies, P.L.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEU:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL'>PEU</scene>

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </td></tr>

~~Description~~: ~~Crystal structure of calpain~~-~~3 penta-EF~~-hand ~~domain~~

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4okh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4okh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4okh RCSB], [http://www.ebi.ac.uk/pdbsum/4okh PDBsum]</td></tr>

<table>

== Disease ==

[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease.

__TOC__

</StructureSection>

[[Category: Calpain-3]]

[[Category: Allingham, J S.]]

[[Category: Campbell, R L.]]

[[Category: Davies, P L.]]

[[Category: Partha, S Karunan.]]

[[Category: Ravulapalli, R.]]

[[Category: Calcium-binding]]

[[Category: Ef-hand]]

[[Category: Hydrolase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of calpain-3 penta-EF-hand domain==
+<StructureSection load='4okh' size='340' side='right' caption='[[4okh]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
-The entry 4okh is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4okh]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OKH FirstGlance]. <br>
-Authors: Karunan Partha, S., Ravulapalli, R., Campbell, R.L., Allingham, J.S., Davies, P.L.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEU:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL'>PEU</scene><br>
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calpain-3 Calpain-3], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.54 3.4.22.54] </span></td></tr>
-Description: Crystal structure of calpain-3 penta-EF-hand domain
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4okh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4okh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4okh RCSB], [http://www.ebi.ac.uk/pdbsum/4okh PDBsum]</span></td></tr>
+<table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Autosomal recessive limb girdle muscular dystrophy type 2A. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/CAN3_HUMAN CAN3_HUMAN]] Calcium-regulated non-lysosomal thiol-protease.
+__TOC__
+</StructureSection>
+[[Category: Calpain-3]]
+[[Category: Allingham, J S.]]
+[[Category: Campbell, R L.]]
+[[Category: Davies, P L.]]
+[[Category: Partha, S Karunan.]]
+[[Category: Ravulapalli, R.]]
+[[Category: Calcium-binding]]
+[[Category: Ef-hand]]
+[[Category: Hydrolase]]