4n9m: Difference between revisions

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{{STRUCTURE_4n9m|  PDB=4n9m  |  SCENE=  }}  
{{STRUCTURE_4n9m|  PDB=4n9m  |  SCENE=  }}  
===Joint neutron/x-ray structure of urate oxidase in complex with 8-hydroxyxanthine===
===Joint neutron/x-ray structure of urate oxidase in complex with 8-hydroxyxanthine===
{{ABSTRACT_PUBMED_19586953}}
{{ABSTRACT_PUBMED_24466188}}


==Function==
==Function==
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==Reference==
==Reference==
<ref group="xtra">PMID:019586953</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024466188</ref><references group="xtra"/><references/>
[[Category: Factor independent urate hydroxylase]]
[[Category: Factor independent urate hydroxylase]]
[[Category: Blakeley, M P.]]
[[Category: Blakeley, M P.]]

Revision as of 14:41, 3 March 2014

Template:STRUCTURE 4n9m

Joint neutron/x-ray structure of urate oxidase in complex with 8-hydroxyxanthine

Template:ABSTRACT PUBMED 24466188

Function

[URIC_ASPFL] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

About this Structure

4n9m is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  1. Oksanen E, Blakeley MP, El-Hajji M, Ryde U, Budayova-Spano M. The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation. PLoS One. 2014 Jan 23;9(1):e86651. doi: 10.1371/journal.pone.0086651. eCollection, 2014 Jan 23. PMID:24466188 doi:https://dx.doi.org/10.1371/journal.pone.0086651

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