3biu: Difference between revisions

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[[Image:3biu.jpg|left|200px]]<br /><applet load="3biu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3biu.jpg|left|200px]]
caption="3biu, resolution 2.3&Aring;" />
 
'''Human thrombin-in complex with UB-THR10'''<br />
{{Structure
|PDB= 3biu |SIZE=350|CAPTION= <scene name='initialview01'>3biu</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=10U:'>10U</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''Human thrombin-in complex with UB-THR10'''
 


==About this Structure==
==About this Structure==
3BIU is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=10U:'>10U</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BIU OCA].  
3BIU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BIU OCA].  


==Reference==
==Reference==
Thermodynamic inhibition profile of a cyclopentyl and a cyclohexyl derivative towards thrombin: the same but for different reasons., Gerlach C, Smolinski M, Steuber H, Sotriffer CA, Heine A, Hangauer DG, Klebe G, Angew Chem Int Ed Engl. 2007;46(44):8511-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17902081 17902081]
Thermodynamic inhibition profile of a cyclopentyl and a cyclohexyl derivative towards thrombin: the same but for different reasons., Gerlach C, Smolinski M, Steuber H, Sotriffer CA, Heine A, Hangauer DG, Klebe G, Angew Chem Int Ed Engl. 2007;46(44):8511-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17902081 17902081]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: blood coagulation]]
[[Category: blood coagulation]]
[[Category: calcium]]
[[Category: calcium]]
[[Category: cleavage on pair of basic residues]]
[[Category: cleavage on pair of basic residue]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: complex (serine protease/inhibitor)]]
[[Category: disease mutation]]
[[Category: disease mutation]]
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[[Category: zymogen]]
[[Category: zymogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:06:05 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:59:21 2008''
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