4co8: Difference between revisions
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==Structure of the DNA binding ETS domain of human ETV4== | |||
<StructureSection load='4co8' size='340' side='right' caption='[[4co8]], [[Resolution|resolution]] 1.05Å' scene=''> | |||
== Structural highlights == | |||
==Disease== | <table><tr><td colspan='2'>[[4co8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CO8 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4co8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4co8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4co8 RCSB], [http://www.ebi.ac.uk/pdbsum/4co8 PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Ewing sarcoma. | [[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Ewing sarcoma. | ||
== Function == | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.<ref>PMID:19307308</ref> | [[http://www.uniprot.org/uniprot/ETV4_HUMAN ETV4_HUMAN]] Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.<ref>PMID:19307308</ref> | ||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
<references | [[Category: Arrowsmith, C H]] | ||
[[Category: Arrowsmith, C H | [[Category: Bountra, C]] | ||
[[Category: Bountra, C | [[Category: Burgess-Brown, N]] | ||
[[Category: Burgess-Brown, N | [[Category: Cooper, C D.O]] | ||
[[Category: Cooper, C D.O | [[Category: Delft, F von]] | ||
[[Category: Delft, F von | [[Category: Edwards, A M]] | ||
[[Category: Edwards, A M | [[Category: Gileadi, O]] | ||
[[Category: Gileadi, O | [[Category: Kopec, J]] | ||
[[Category: Kopec, J | [[Category: Newman, J A]] | ||
[[Category: Newman, J A | [[Category: Shrestha, L]] | ||
[[Category: Shrestha, L | |||
[[Category: Transcription]] | [[Category: Transcription]] | ||
