4icc: Difference between revisions
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{{STRUCTURE_4icc| PDB=4icc | SCENE= }} | |||
===Crystal structure of human AKR1B10 complexed with NADP+ and JF0064=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/AK1BA_HUMAN AK1BA_HUMAN]] Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.<ref>PMID:18087047</ref> | |||
==About this Structure== | |||
[[4icc]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ICC OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Cousido-Siah, A.]] | |||
[[Category: Farres, J.]] | |||
[[Category: Fuente, J A.de la.]] | |||
[[Category: Klebe, G.]] | |||
[[Category: Lera, A R.de.]] | |||
[[Category: Martin, M J.]] | |||
[[Category: Mitschler, A.]] | |||
[[Category: Pares, X.]] | |||
[[Category: Podjarny, A.]] | |||
[[Category: Porte, S.]] | |||
[[Category: Ruiz, F X.]] | |||
[[Category: Aldo-keto reductase]] | |||
[[Category: Cytosolic]] | |||
[[Category: Halogenated compound]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
[[Category: Tim barrel]] | |||
Revision as of 17:45, 19 February 2014
Crystal structure of human AKR1B10 complexed with NADP+ and JF0064
Function
[AK1BA_HUMAN] Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.[1]
About this Structure
4icc is a 1 chain structure. Full crystallographic information is available from OCA.
