3c6m: Difference between revisions

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[[Image:3c6m.jpg|left|200px]]<br /><applet load="3c6m" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3c6m.jpg|left|200px]]
caption="3c6m, resolution 2.45&Aring;" />
 
'''Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine'''<br />
{{Structure
|PDB= 3c6m |SIZE=350|CAPTION= <scene name='initialview01'>3c6m</scene>, resolution 2.45&Aring;
|SITE= <scene name='pdbsite=AC1:Spm+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+501'>AC2</scene>, <scene name='pdbsite=AC3:Spm+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Spm+Binding+Site+For+Residue+D+501'>AC4</scene>, <scene name='pdbsite=AC5:Mta+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Mta+Binding+Site+For+Residue+B+401'>AC6</scene>, <scene name='pdbsite=AC7:Mta+Binding+Site+For+Residue+C+401'>AC7</scene> and <scene name='pdbsite=AC8:Mta+Binding+Site+For+Residue+D+401'>AC8</scene>
|LIGAND= <scene name='pdbligand=SPM:SPERMINE'>SPM</scene> and <scene name='pdbligand=MTA:5'-DEOXY-5'-METHYLTHIOADENOSINE'>MTA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Spermine_synthase Spermine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.22 2.5.1.22]
|GENE= SMS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine'''
 


==About this Structure==
==About this Structure==
3C6M is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SPM:'>SPM</scene> and <scene name='pdbligand=MTA:'>MTA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Spermine_synthase Spermine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.22 2.5.1.22] Known structural/functional Sites: <scene name='pdbsite=AC1:Spm+Binding+Site+For+Residue+A+501'>AC1</scene>, <scene name='pdbsite=AC2:Spm+Binding+Site+For+Residue+B+501'>AC2</scene>, <scene name='pdbsite=AC3:Spm+Binding+Site+For+Residue+C+501'>AC3</scene>, <scene name='pdbsite=AC4:Spm+Binding+Site+For+Residue+D+501'>AC4</scene>, <scene name='pdbsite=AC5:Mta+Binding+Site+For+Residue+A+401'>AC5</scene>, <scene name='pdbsite=AC6:Mta+Binding+Site+For+Residue+B+401'>AC6</scene>, <scene name='pdbsite=AC7:Mta+Binding+Site+For+Residue+C+401'>AC7</scene> and <scene name='pdbsite=AC8:Mta+Binding+Site+For+Residue+D+401'>AC8</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6M OCA].  
3C6M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6M OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 26: Line 35:
[[Category: spermidine aminopropyltransferase]]
[[Category: spermidine aminopropyltransferase]]
[[Category: spmsy]]
[[Category: spmsy]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:34 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:02:50 2008''

Revision as of 17:02, 20 March 2008

File:3c6m.jpg


Drag the structure with the mouse to rotate
3c6m, resolution 2.45Å
Sites: AC1, AC2, AC3, AC4, AC5, AC6, AC7 and AC8
Ligands: SPM and MTA
Gene: SMS (Homo sapiens)
Activity: Spermine synthase, with EC number 2.5.1.22
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine


About this Structure

3C6M is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 19:02:50 2008

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