4obq: Difference between revisions
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{{STRUCTURE_4obq| PDB=4obq | SCENE= }} | |||
===MAP4K4 in complex with inhibitor (compound 31), N-[3-(4-AMINOQUINAZOLIN-6-YL)-5-FLUOROPHENYL]-2-(PYRROLIDIN-1-YL)ACETAMIDE=== | |||
{{ABSTRACT_PUBMED_24673130}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/M4K4_HUMAN M4K4_HUMAN]] Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.<ref>PMID:9890973</ref> <ref>PMID:21690388</ref> | |||
==About this Structure== | |||
[[4obq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBQ OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024673130</ref><references group="xtra"/><references/> | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Coons, M.]] | |||
[[Category: Harris, S F.]] | |||
[[Category: Wu, P.]] | |||
[[Category: Kinase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||