4obq: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4obq|  PDB=4obq  |  SCENE=  }}
===MAP4K4 in complex with inhibitor (compound 31), N-[3-(4-AMINOQUINAZOLIN-6-YL)-5-FLUOROPHENYL]-2-(PYRROLIDIN-1-YL)ACETAMIDE===
{{ABSTRACT_PUBMED_24673130}}


The entry 4obq is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/M4K4_HUMAN M4K4_HUMAN]] Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.<ref>PMID:9890973</ref> <ref>PMID:21690388</ref>  


Authors: Harris, S.F., Wu, P., Coons, M.
==About this Structure==
[[4obq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OBQ OCA].  


Description:
==Reference==
<ref group="xtra">PMID:024673130</ref><references group="xtra"/><references/>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Coons, M.]]
[[Category: Harris, S F.]]
[[Category: Wu, P.]]
[[Category: Kinase]]
[[Category: Transferase-transferase inhibitor complex]]