3ert: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:3ert.gif|left|200px]]<br /><applet load="3ert" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3ert.gif|left|200px]]
caption="3ert, resolution 1.90&Aring;" />
 
'''HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN'''<br />
{{Structure
|PDB= 3ert |SIZE=350|CAPTION= <scene name='initialview01'>3ert</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene>
|ACTIVITY=
|GENE= ESTROGEN RECEPTOR ALPHA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN'''
 


==Overview==
==Overview==
Line 10: Line 19:


==About this Structure==
==About this Structure==
3ERT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=OHT:'>OHT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 2ERT. The following page contains interesting information on the relation of 3ERT with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb45_1.html Estrogen Receptor]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ERT OCA].  
3ERT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 2ERT. The following page contains interesting information on the relation of 3ERT with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb45_1.html Estrogen Receptor]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ERT OCA].  


==Reference==
==Reference==
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen., Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, Greene GL, Cell. 1998 Dec 23;95(7):927-37. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9875847 9875847]
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen., Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, Greene GL, Cell. 1998 Dec 23;95(7):927-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9875847 9875847]
[[Category: Estrogen Receptor]]
[[Category: Estrogen Receptor]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 30: Line 39:
[[Category: transcription factor]]
[[Category: transcription factor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:09:16 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:04:39 2008''