4osx: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===STRUCTURE of UNCLEAVED GLYCINE-BOUND HUMAN L-ASPARAGINASE PROTEIN===

~~The entry 4osx~~ is ~~ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/ASGL1_HUMAN ASGL1_HUMAN]] Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.<ref>PMID:19839645</ref>

~~Authors~~: ~~Nomme, J~~.~~, Lavie, A~~.

==About this Structure==

[[4osx]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4hlo 4hlo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OSX OCA].

~~Description~~: ~~STRUCTURE OF UNCLEAVED GLYCINE-BOUND HUMAN L-ASPARAGINASE PROTEIN~~

==Reference==

[[Category: Lavie, A.]]

[[Category: Nomme, J.]]

[[Category: Hydrolase]]

[[Category: Ntn enzyme]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4osx|  PDB=4osx  |  SCENE=  }}
+===STRUCTURE of UNCLEAVED GLYCINE-BOUND HUMAN L-ASPARAGINASE PROTEIN===
+{{ABSTRACT_PUBMED_23601642}}
-The entry 4osx is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/ASGL1_HUMAN ASGL1_HUMAN]] Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.<ref>PMID:19839645</ref>
-Authors: Nomme, J., Lavie, A.
+==About this Structure==
+[[4osx]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4hlo 4hlo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OSX OCA].
-Description: STRUCTURE OF UNCLEAVED GLYCINE-BOUND HUMAN L-ASPARAGINASE PROTEIN
+==Reference==
+<ref group="xtra">PMID:023601642</ref><references group="xtra"/><references/>
+[[Category: Lavie, A.]]
+[[Category: Nomme, J.]]
+[[Category: Hydrolase]]
+[[Category: Ntn enzyme]]