3por: Difference between revisions
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[[Image:3por.jpg|left|200px]] | [[Image:3por.jpg|left|200px]] | ||
'''PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION''' | {{Structure | ||
|PDB= 3por |SIZE=350|CAPTION= <scene name='initialview01'>3por</scene>, resolution 2.5Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=C8E:(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE'>C8E</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
3POR is a [ | 3POR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3POR OCA]. | ||
==Reference== | ==Reference== | ||
Porin conformation in the absence of calcium. Refined structure at 2.5 A resolution., Weiss MS, Schulz GE, J Mol Biol. 1993 Jun 5;231(3):817-24. PMID:[http:// | Porin conformation in the absence of calcium. Refined structure at 2.5 A resolution., Weiss MS, Schulz GE, J Mol Biol. 1993 Jun 5;231(3):817-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7685826 7685826] | ||
[[Category: Rhodobacter capsulatus]] | [[Category: Rhodobacter capsulatus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: integral membrane protein porin]] | [[Category: integral membrane protein porin]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:06:43 2008'' | ||
Revision as of 17:06, 20 March 2008
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| 3por, resolution 2.5Å | |||||||||||||
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| Ligands: | C8E and TRS | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
PORIN CONFORMATION IN THE ABSENCE OF CALCIUM; REFINED STRUCTURE AT 2.5 ANGSTROMS RESOLUTION
Overview
The crystal structure of porin from Rhodobacter capsulatus in the absence of divalent calcium ions has been refined to convergence at a resolution of 2.5 A using the simulated annealing refinement method. The final model consists of all 301 amino acid residues, 77 solvent molecules, one tris(hydroxymethyl)-aminomethane molecule and one unknown ligand modeled as n-octyltetraoxyethylene. A superposition with the previously described model containing three calcium ions showed structural changes at the segment 108-116 of the inner loop beta 5-beta 6, and at loops beta 8-beta 9 and beta 11-beta 12 at the extracellular side of the porin molecule. Evidence is presented that the conformational changes depend on the presence or absence of calcium ions. A possible influence on porin function is discussed.
About this Structure
3POR is a Single protein structure of sequence from Rhodobacter capsulatus. Full crystallographic information is available from OCA.
Reference
Porin conformation in the absence of calcium. Refined structure at 2.5 A resolution., Weiss MS, Schulz GE, J Mol Biol. 1993 Jun 5;231(3):817-24. PMID:7685826
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