4o91: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1==

~~The entry~~ 4o91 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4o91]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O91 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O91 FirstGlance].

~~Authors~~: Gurbani, D., Hunter, J.C., Tan, L., Westover, K.D.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NG2:N-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-(1H-PYRROLO[2,3-B]PYRIDIN-4-YLOXY)BENZAMIDE'>NG2</scene>

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase_kinase_kinase Mitogen-activated protein kinase kinase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.25 2.7.11.25] </td></tr>

~~Description~~: ~~Crystal Structure~~ of ~~type II~~ inhibitor ~~NG25 bound to TAK1-TAB1~~

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o91 RCSB], [http://www.ebi.ac.uk/pdbsum/4o91 PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Mitogen-activated protein kinase kinase kinase]]

[[Category: Gurbani, D.]]

[[Category: Hunter, J C.]]

[[Category: Tan, L.]]

[[Category: Westover, K D.]]

[[Category: Mitogen-activated protein kinase kinase kinase 7]]

[[Category: Serine/threonine kinase which acts as an essential component of the map kinase signal transduction pathway]]

[[Category: Tgf-beta-activated kinase 1 and map3k7-binding protein 1]]

[[Category: Tgf-beta-activated kinase 1 and map3k7-binding protein 1 chimera]]

[[Category: Transferase-transferase inhibitor complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1==
+<StructureSection load='4o91' size='340' side='right' caption='[[4o91]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
-The entry 4o91 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4o91]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O91 FirstGlance]. <br>
-Authors: Gurbani, D., Hunter, J.C., Tan, L., Westover, K.D.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NG2:N-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-(1H-PYRROLO[2,3-B]PYRIDIN-4-YLOXY)BENZAMIDE'>NG2</scene><br>
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase_kinase_kinase Mitogen-activated protein kinase kinase kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.25 2.7.11.25] </span></td></tr>
-Description: Crystal Structure of type II inhibitor NG25 bound to TAK1-TAB1
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o91 RCSB], [http://www.ebi.ac.uk/pdbsum/4o91 PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Mitogen-activated protein kinase kinase kinase]]
+[[Category: Gurbani, D.]]
+[[Category: Hunter, J C.]]
+[[Category: Tan, L.]]
+[[Category: Westover, K D.]]
+[[Category: Mitogen-activated protein kinase kinase kinase 7]]
+[[Category: Serine/threonine kinase which acts as an essential component of the map kinase signal transduction pathway]]
+[[Category: Tgf-beta-activated kinase 1 and map3k7-binding protein 1]]
+[[Category: Tgf-beta-activated kinase 1 and map3k7-binding protein 1 chimera]]
+[[Category: Transferase-transferase inhibitor complex]]