4ps4: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of the complex between IL-13 and M1295 FAB===

~~The~~ entry ~~4ps4~~ is ~~ON HOLD~~

==Disease==

[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.

~~Authors~~: ~~Teplyakov, A~~.~~, Obmolova, G~~.~~, Malia, T~~.~~, Gilliland, G~~.L.

==Function==

[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.

~~Description~~: ~~CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN IL~~-~~13 AND M1295 FAB~~

==About this Structure==

[[4ps4]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l5y 3l5y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PS4 OCA].

==Reference==

[[Category: Gilliland, G L.]]

[[Category: Malia, T.]]

[[Category: Obmolova, G.]]

[[Category: Teplyakov, A.]]

[[Category: Alpha-helical bundle]]

[[Category: Cytokine]]

[[Category: Disulfide bond]]

[[Category: Glycoprotein]]

[[Category: Immune system]]

[[Category: Immunoglobulin fold]]

[[Category: Monoclonal antibody]]

[[Category: Secreted]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4ps4|  PDB=4ps4  |  SCENE=  }}
+===Crystal structure of the complex between IL-13 and M1295 FAB===
+{{ABSTRACT_PUBMED_20226193}}
-The entry 4ps4 is ON HOLD
+==Disease==
+[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
-Authors: Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L.
+==Function==
+[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
-Description: CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN IL-13 AND M1295 FAB
+==About this Structure==
+[[4ps4]] is a 3 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l5y 3l5y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PS4 OCA].
+==Reference==
+<ref group="xtra">PMID:020226193</ref><references group="xtra"/><references/>
+[[Category: Gilliland, G L.]]
+[[Category: Malia, T.]]
+[[Category: Obmolova, G.]]
+[[Category: Teplyakov, A.]]
+[[Category: Alpha-helical bundle]]
+[[Category: Cytokine]]
+[[Category: Disulfide bond]]
+[[Category: Glycoprotein]]
+[[Category: Immune system]]
+[[Category: Immunoglobulin fold]]
+[[Category: Monoclonal antibody]]
+[[Category: Secreted]]