4gss: Difference between revisions

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[[Image:4gss.jpg|left|200px]]<br /><applet load="4gss" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:4gss.jpg|left|200px]]
caption="4gss, resolution 2.5&Aring;" />
 
'''HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y108F MUTANT'''<br />
{{Structure
|PDB= 4gss |SIZE=350|CAPTION= <scene name='initialview01'>4gss</scene>, resolution 2.5&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GTX:S-HEXYLGLUTATHIONE'>GTX</scene> and <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC ACID'>MES</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]
|GENE= GTP_HUMAN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y108F MUTANT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
4GSS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GTX:'>GTX</scene> and <scene name='pdbligand=MES:'>MES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSS OCA].  
4GSS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GSS OCA].  


==Reference==
==Reference==
Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme., Lo Bello M, Oakley AJ, Battistoni A, Mazzetti AP, Nuccetelli M, Mazzarese G, Rossjohn J, Parker MW, Ricci G, Biochemistry. 1997 May 20;36(20):6207-17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9166793 9166793]
Multifunctional role of Tyr 108 in the catalytic mechanism of human glutathione transferase P1-1. Crystallographic and kinetic studies on the Y108F mutant enzyme., Lo Bello M, Oakley AJ, Battistoni A, Mazzetti AP, Nuccetelli M, Mazzarese G, Rossjohn J, Parker MW, Ricci G, Biochemistry. 1997 May 20;36(20):6207-17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9166793 9166793]
[[Category: Glutathione transferase]]
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: transferase]]
[[Category: transferase]]


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