4or2: Difference between revisions

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{{STRUCTURE_4or2|  PDB=4or2  |  SCENE=  }}
==Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator==
===Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator===
<StructureSection load='4or2' size='340' side='right' caption='[[4or2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4or2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OR2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=FM9:4-FLUORO-N-METHYL-N-{4-[6-(PROPAN-2-YLAMINO)PYRIMIDIN-4-YL]-1,3-THIAZOL-2-YL}BENZAMIDE'>FM9</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cybC, GRM1_HUMAN, GPRC1A, GRM1, MGLUR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4or2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4or2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4or2 RCSB], [http://www.ebi.ac.uk/pdbsum/4or2 PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX]] Electron-transport protein of unknown function.  
[[http://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX]] Electron-transport protein of unknown function.  
==About this Structure==
[[4or2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OR2 OCA].


==See Also==
==See Also==
*[[G protein-coupled receptor|G protein-coupled receptor]]
*[[Metabotropic glutamate receptor|Metabotropic glutamate receptor]]
*[[Metabotropic glutamate receptor|Metabotropic glutamate receptor]]
[[Category: Cherezov, V.]]
__TOC__
[[Category: Cho, H P.]]
</StructureSection>
[[Category: Conn, P J.]]
[[Category: Bacillus coli migula 1895]]
[[Category: GPCR, GPCR Network.]]
[[Category: Cherezov, V]]
[[Category: Gregory, K J.]]
[[Category: Cho, H P]]
[[Category: Han, G W.]]
[[Category: Conn, P J]]
[[Category: Katritch, V.]]
[[Category: GPCR, GPCR Network]]
[[Category: Niswender, C M.]]
[[Category: Gregory, K J]]
[[Category: Stevens, R C.]]
[[Category: Han, G W]]
[[Category: Wang, C.]]
[[Category: Katritch, V]]
[[Category: Wu, H.]]
[[Category: Niswender, C M]]
[[Category: Xia, Y.]]
[[Category: Stevens, R C]]
[[Category: Wang, C]]
[[Category: Wu, H]]
[[Category: Xia, Y]]
[[Category: Allosteric modulator]]
[[Category: Allosteric modulator]]
[[Category: Gpcr]]
[[Category: Gpcr]]

Revision as of 15:41, 24 December 2014

Human class C G protein-coupled metabotropic glutamate receptor 1 in complex with a negative allosteric modulator

4or2, resolution 2.80Å

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