6upj: Difference between revisions

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[[Image:6upj.jpg|left|200px]]<br /><applet load="6upj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:6upj.jpg|left|200px]]
caption="6upj, resolution 2.34&Aring;" />
 
'''HIV-2 PROTEASE/U99294 COMPLEX'''<br />
{{Structure
|PDB= 6upj |SIZE=350|CAPTION= <scene name='initialview01'>6upj</scene>, resolution 2.34&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NIU:6,7,8,9-TETRAHYDRO-4-HYDROXY-3-(1-PHENYLPROPYL)CYCLOHEPTA[B]PYRAN-2-ONE'>NIU</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
|GENE=
}}
 
'''HIV-2 PROTEASE/U99294 COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
6UPJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=NIU:'>NIU</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UPJ OCA].  
6UPJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UPJ OCA].  


==Reference==
==Reference==
Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors., Romines KR, Watenpaugh KD, Tomich PK, Howe WJ, Morris JK, Lovasz KD, Mulichak AM, Finzel BC, Lynn JC, Horng MM, et al., J Med Chem. 1995 May 26;38(11):1884-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7783120 7783120]
Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors., Romines KR, Watenpaugh KD, Tomich PK, Howe WJ, Morris JK, Lovasz KD, Mulichak AM, Finzel BC, Lynn JC, Horng MM, et al., J Med Chem. 1995 May 26;38(11):1884-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7783120 7783120]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: protein-substrate interaction]]
[[Category: protein-substrate interaction]]


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