4ctj: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4ctj|  PDB=4ctj  |  SCENE=  }}
===DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND FRAGMENT 3A9===
{{ABSTRACT_PUBMED_24704437}}


The entry 4ctj is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/A9LIE0_9FLAV A9LIE0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS013754_004_099774]


Authors: Barral, K., Bricogne, G., Sharff, A.
==About this Structure==
[[4ctj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CTJ OCA].  


Description: DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND FRAGMENT 3A9
==Reference==
<ref group="xtra">PMID:024704437</ref><references group="xtra"/><references/>
[[Category: Barral, K.]]
[[Category: Bricogne, G.]]
[[Category: Sharff, A.]]
[[Category: Antiviral screening]]
[[Category: Fragment-based drug discovery]]
[[Category: Ns5 methyltransferase]]
[[Category: Transferase]]