4k0n: Difference between revisions
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{{STRUCTURE_4k0n| PDB=4k0n | SCENE= }} | |||
===Crystal structure of human CLIC1 C24A mutant=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN]] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref> | |||
==About this Structure== | |||
[[4k0n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0N OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Curmi, P M.G.]] | |||
[[Category: Duff, A P.]] | |||
[[Category: Harrop, S J.]] | |||
[[Category: Phang, J M.]] | |||
[[Category: Wilk, K E.]] | |||
[[Category: Chloride ion channel]] | |||
[[Category: Clic]] | |||
[[Category: Glutathione-s-transferase fold]] | |||
[[Category: Transport protein]] | |||