Sandbox Reserved 911: Difference between revisions
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FAAH requires two water molecules in its active site to properly position and cleave amide bonds. One water molecule (W1) deacylates the substrate, and the other (W2) helps coordinate W1 through the catalytic K142. (3LJ6) | FAAH requires two water molecules in its active site to properly position and cleave amide bonds. One water molecule (W1) deacylates the substrate, and the other (W2) helps coordinate W1 through the catalytic K142. (3LJ6) | ||
[[Image:Catalytic_triad2.png| | [[Image:Catalytic_triad2.png|1500px|left|Catalytic Triad]] | ||
==Relationship to other proteins== | ==Relationship to other proteins== | ||
