9est: Difference between revisions

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[[Image:9est.gif|left|200px]]<br /><applet load="9est" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:9est.gif|left|200px]]
caption="9est, resolution 1.9&Aring;" />
 
'''STRUCTURAL STUDY OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH 7-AMINO-3-(2-BROMOETHOXY)-4-CHLOROISOCOUMARIN AS A NONREACTIVATABLE DOUBLY COVALENT ENZYME-INHIBITOR COMPLEX'''<br />
{{Structure
|PDB= 9est |SIZE=350|CAPTION= <scene name='initialview01'>9est</scene>, resolution 1.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=IBR:(2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATE'>IBR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36]
|GENE=
}}
 
'''STRUCTURAL STUDY OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH 7-AMINO-3-(2-BROMOETHOXY)-4-CHLOROISOCOUMARIN AS A NONREACTIVATABLE DOUBLY COVALENT ENZYME-INHIBITOR COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
9EST is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=IBR:'>IBR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EST OCA].  
9EST is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EST OCA].  


==Reference==
==Reference==
Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex., Vijayalakshmi J, Meyer EF Jr, Kam CM, Powers JC, Biochemistry. 1991 Feb 26;30(8):2175-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1998677 1998677]
Structural study of porcine pancreatic elastase complexed with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin as a nonreactivatable doubly covalent enzyme-inhibitor complex., Vijayalakshmi J, Meyer EF Jr, Kam CM, Powers JC, Biochemistry. 1991 Feb 26;30(8):2175-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1998677 1998677]
[[Category: Pancreatic elastase]]
[[Category: Pancreatic elastase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydrolase(serine proteinase)]]
[[Category: hydrolase(serine proteinase)]]


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