2ra3: Difference between revisions

[[Image:2ra3.jpg|left|200px]]<br /><applet load="2ra3" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2ra3, resolution 1.46&Aring;" />

'''Human cationic trypsin complexed with bovine pancreatic trypsin inhibitor (BPTI)'''<br />

2RA3 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Known structural/functional Sites: <scene name='pdbsite=AC1:Ca+Binding+Site+For+Residue+A+1'>AC1</scene>, <scene name='pdbsite=AC2:So4+Binding+Site+For+Residue+A+6'>AC2</scene>, <scene name='pdbsite=AC3:So4+Binding+Site+For+Residue+A+10'>AC3</scene>, <scene name='pdbsite=AC4:So4+Binding+Site+For+Residue+A+12'>AC4</scene>, <scene name='pdbsite=AC5:So4+Binding+Site+For+Residue+A+14'>AC5</scene>, <scene name='pdbsite=AC6:So4+Binding+Site+For+Residue+A+247'>AC6</scene>, <scene name='pdbsite=AC7:So4+Binding+Site+For+Residue+A+248'>AC7</scene>, <scene name='pdbsite=AC8:So4+Binding+Site+For+Residue+A+249'>AC8</scene>, <scene name='pdbsite=AC9:Ca+Binding+Site+For+Residue+B+1'>AC9</scene>, <scene name='pdbsite=BC1:So4+Binding+Site+For+Residue+B+4'>BC1</scene>, <scene name='pdbsite=BC2:So4+Binding+Site+For+Residue+B+5'>BC2</scene>, <scene name='pdbsite=BC3:So4+Binding+Site+For+Residue+B+7'>BC3</scene>, <scene name='pdbsite=BC4:So4+Binding+Site+For+Residue+B+8'>BC4</scene>, <scene name='pdbsite=BC5:So4+Binding+Site+For+Residue+B+11'>BC5</scene>, <scene name='pdbsite=BC6:So4+Binding+Site+For+Residue+B+15'>BC6</scene>, <scene name='pdbsite=BC7:So4+Binding+Site+For+Residue+B+247'>BC7</scene>, <scene name='pdbsite=BC8:So4+Binding+Site+For+Residue+B+248'>BC8</scene>, <scene name='pdbsite=BC9:So4+Binding+Site+For+Residue+B+249'>BC9</scene>, <scene name='pdbsite=CC1:So4+Binding+Site+For+Residue+B+250'>CC1</scene>, <scene name='pdbsite=CC2:So4+Binding+Site+For+Residue+I+59'>CC2</scene>, <scene name='pdbsite=CC3:So4+Binding+Site+For+Residue+I+60'>CC3</scene>, <scene name='pdbsite=CC4:So4+Binding+Site+For+Residue+I+61'>CC4</scene>, <scene name='pdbsite=CC5:So4+Binding+Site+For+Residue+I+62'>CC5</scene>, <scene name='pdbsite=CC6:So4+Binding+Site+For+Residue+I+63'>CC6</scene>, <scene name='pdbsite=CC7:So4+Binding+Site+For+Residue+C+59'>CC7</scene> and <scene name='pdbsite=CC8:So4+Binding+Site+For+Residue+C+60'>CC8</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RA3 OCA].  

Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin., Salameh MA, Soares AS, Hockla A, Radisky ES, J Biol Chem. 2008 Feb 15;283(7):4115-23. Epub 2007 Dec 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18077447 18077447]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 27 07:47:59 2008''