Ricin: Difference between revisions
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Ricin also triggers apoptosis <ref name="Tesh">PMID: 22130961</ref>, though the exact pathway is a current research topic. There is some evidence that it occurs via the B subunit <ref name="Yermakova">PMID: 22984492</ref>, though there is also evidence that the protein synthesis inhibition may cause apoptosis <ref name="Jetzt">PMID: 22982239</ref>. | Ricin also triggers apoptosis <ref name="Tesh">PMID: 22130961</ref>, though the exact pathway is a current research topic. There is some evidence that it occurs via the B subunit <ref name="Yermakova">PMID: 22984492</ref>, though there is also evidence that the protein synthesis inhibition may cause apoptosis <ref name="Jetzt">PMID: 22982239</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of ricin== | |||
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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[[1j1m]], [[1ift]], [[2aai]], [[1rtc]] – RTA<br /> | [[1j1m]], [[1ift]], [[2aai]], [[1rtc]] – RTA<br /> | ||
[[3lc9]], [[3mk9]], [[2vc4]], [[1uq4]], [[1uq5]], [[1obs]], [[3bjg]], [[3srp]] – RTA (mutant) | [[3lc9]], [[3mk9]], [[2vc4]], [[1uq4]], [[1uq5]], [[1obs]], [[3bjg]], [[3srp]], [[4imv]] – RTA (mutant) | ||
__notoc__ | __notoc__ | ||
===Ricin A chain binary complexes=== | ===Ricin A chain binary complexes=== | ||
[[3px8]] – RTA preproricin + 7-carboxy-pterin<br /> | [[3px8]] – RTA preproricin + 7-carboxy-pterin<br /> | ||
[[1br5]], [[1br6]] - RTA + pterin derivative<br /> | [[1br5]], [[1br6]], [[4esi]], [[4huo]], [[4hup]], [[4hv3]], [[4hv7]], [[4mx1]], [[4mx5]] - RTA + pterin derivative<br /> | ||
[[3px9]] - RTA preproricin + furanylmethyl-carbamoyl-pterin<br /> | [[3px9]] - RTA preproricin + furanylmethyl-carbamoyl-pterin<br /> | ||
[[3lc9]], [[3mk9]], [[2vc4]], [[1uq4]], [[1uq5]], [[1obs]] – RTA (mutant) <br /> | [[3lc9]], [[3mk9]], [[2vc4]], [[1uq4]], [[1uq5]], [[1obs]] – RTA (mutant) <br /> | ||
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===Ricin A+B chains=== | ===Ricin A+B chains=== | ||
[[2aai]] - RTA + RTB | [[2aai]] - RTA + RTB<br /> | ||
[[3px8]], [[3rti]] – RTA + RTB + formycin monophosphate<br /> | |||
[[3rtj]] - RTA + RTB + dinucleotide | [[3rtj]] - RTA + RTB + dinucleotide | ||
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==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
[[Category: Topic Page]] | |||
