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New page: left|200px<br /><applet load="2pmu" size="350" color="white" frame="true" align="right" spinBox="true" caption="2pmu, resolution 1.779Å" /> '''Crystal structure o...
 
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[[Image:2pmu.jpg|left|200px]]<br /><applet load="2pmu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2pmu.jpg|left|200px]]
caption="2pmu, resolution 1.779&Aring;" />
 
'''Crystal structure of the DNA-binding domain of PhoP'''<br />
{{Structure
|PDB= 2pmu |SIZE=350|CAPTION= <scene name='initialview01'>2pmu</scene>, resolution 1.779&Aring;
|SITE= <scene name='pdbsite=AC1:Po4+Binding+Site+For+Residue+D+1001'>AC1</scene>, <scene name='pdbsite=AC2:Po4+Binding+Site+For+Residue+D+1002'>AC2</scene>, <scene name='pdbsite=AC3:Po4+Binding+Site+For+Residue+E+1003'>AC3</scene>, <scene name='pdbsite=AC4:Po4+Binding+Site+For+Residue+A+1004'>AC4</scene>, <scene name='pdbsite=AC5:K+Binding+Site+For+Residue+D+2001'>AC5</scene>, <scene name='pdbsite=AC6:K+Binding+Site+For+Residue+A+2002'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+E+2003'>AC7</scene>, <scene name='pdbsite=AC8:Cl+Binding+Site+For+Residue+E+3001'>AC8</scene>, <scene name='pdbsite=AC9:Cl+Binding+Site+For+Residue+D+3004'>AC9</scene>, <scene name='pdbsite=BC1:GLY+Binding+Site+For+Residue+B+4001'>BC1</scene>, <scene name='pdbsite=BC2:GLY+Binding+Site+For+Residue+B+4002'>BC2</scene>, <scene name='pdbsite=BC3:GLY+Binding+Site+For+Residue+B+4003'>BC3</scene>, <scene name='pdbsite=BC4:Unx+Binding+Site+For+Residue+E+5001'>BC4</scene>, <scene name='pdbsite=BC5:Unx+Binding+Site+For+Residue+B+5002'>BC5</scene>, <scene name='pdbsite=BC6:Unx+Binding+Site+For+Residue+D+6001'>BC6</scene> and <scene name='pdbsite=BC7:Unx+Binding+Site+For+Residue+A+6002'>BC7</scene>
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene> and <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>
|ACTIVITY=
|GENE= PhoP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal structure of the DNA-binding domain of PhoP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2PMU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=UNX:'>UNX</scene> and <scene name='pdbligand=GLY:'>GLY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Po4+Binding+Site+For+Residue+D+1001'>AC1</scene>, <scene name='pdbsite=AC2:Po4+Binding+Site+For+Residue+D+1002'>AC2</scene>, <scene name='pdbsite=AC3:Po4+Binding+Site+For+Residue+E+1003'>AC3</scene>, <scene name='pdbsite=AC4:Po4+Binding+Site+For+Residue+A+1004'>AC4</scene>, <scene name='pdbsite=AC5:K+Binding+Site+For+Residue+D+2001'>AC5</scene>, <scene name='pdbsite=AC6:K+Binding+Site+For+Residue+A+2002'>AC6</scene>, <scene name='pdbsite=AC7:K+Binding+Site+For+Residue+E+2003'>AC7</scene>, <scene name='pdbsite=AC8:Cl+Binding+Site+For+Residue+E+3001'>AC8</scene>, <scene name='pdbsite=AC9:Cl+Binding+Site+For+Residue+D+3004'>AC9</scene>, <scene name='pdbsite=BC1:GLY+Binding+Site+For+Residue+B+4001'>BC1</scene>, <scene name='pdbsite=BC2:GLY+Binding+Site+For+Residue+B+4002'>BC2</scene>, <scene name='pdbsite=BC3:GLY+Binding+Site+For+Residue+B+4003'>BC3</scene>, <scene name='pdbsite=BC4:Unx+Binding+Site+For+Residue+E+5001'>BC4</scene>, <scene name='pdbsite=BC5:Unx+Binding+Site+For+Residue+B+5002'>BC5</scene>, <scene name='pdbsite=BC6:Unx+Binding+Site+For+Residue+D+6001'>BC6</scene> and <scene name='pdbsite=BC7:Unx+Binding+Site+For+Residue+A+6002'>BC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMU OCA].  
2PMU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PMU OCA].  


==Reference==
==Reference==
Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis., Wang S, Engohang-Ndong J, Smith I, Biochemistry. 2007 Dec 25;46(51):14751-61. Epub 2007 Dec 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18052041 18052041]
Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis., Wang S, Engohang-Ndong J, Smith I, Biochemistry. 2007 Dec 25;46(51):14751-61. Epub 2007 Dec 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18052041 18052041]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: winged helix-tun-helx]]
[[Category: winged helix-tun-helx]]


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