2rdw: Difference between revisions

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New page: left|200px<br /><applet load="2rdw" size="350" color="white" frame="true" align="right" spinBox="true" caption="2rdw, resolution 1.950Å" /> '''Crystal Structure o...
 
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[[Image:2rdw.jpg|left|200px]]<br /><applet load="2rdw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2rdw.jpg|left|200px]]
caption="2rdw, resolution 1.950&Aring;" />
 
'''Crystal Structure of Human Glycolate Oxidase in Complex with Sulfate'''<br />
{{Structure
|PDB= 2rdw |SIZE=350|CAPTION= <scene name='initialview01'>2rdw</scene>, resolution 1.950&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+371'>AC1</scene> and <scene name='pdbsite=AC2:Fmn+Binding+Site+For+Residue+A+372'>AC2</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=FMN:FLAVIN MONONUCLEOTIDE'>FMN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15]
|GENE= HAO1, GOX1, HAOX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of Human Glycolate Oxidase in Complex with Sulfate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2RDW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=FMN:'>FMN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+371'>AC1</scene> and <scene name='pdbsite=AC2:Fmn+Binding+Site+For+Residue+A+372'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDW OCA].  
2RDW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RDW OCA].  


==Reference==
==Reference==
Active Site and Loop 4 Movements within Human Glycolate Oxidase: Implications for Substrate Specificity and Drug Design., Murray MS, Holmes RP, Lowther WT, Biochemistry. 2008 Feb 26;47(8):2439-49. Epub 2008 Jan 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18215067 18215067]
Active Site and Loop 4 Movements within Human Glycolate Oxidase: Implications for Substrate Specificity and Drug Design., Murray MS, Holmes RP, Lowther WT, Biochemistry. 2008 Feb 26;47(8):2439-49. Epub 2008 Jan 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18215067 18215067]
[[Category: (S)-2-hydroxy-acid oxidase]]
[[Category: (S)-2-hydroxy-acid oxidase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: peroxisome]]
[[Category: peroxisome]]


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