4p90: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of the kinase domain of human PAK1 in complex with compound 15==

~~The entry~~ 4p90 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4p90]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P90 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P90 FirstGlance].

~~Authors~~: Ferguson, A.D.

</td></tr><tr><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=2K0:[2-CHLORO-5-(HYDROXYMETHYL)PHENYL]{5-[1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}METHANONE'>2K0</scene>

<tr><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </td></tr>

~~Description~~: ~~Crystal structure of the kinase domain of human PAK1 in~~ complex ~~with compound 15~~

<tr><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p90 RCSB], [http://www.ebi.ac.uk/pdbsum/4p90 PDBsum]</td></tr>

<table>

__TOC__

</StructureSection>

[[Category: Non-specific serine/threonine protein kinase]]

[[Category: Ferguson, A D.]]

[[Category: Inhibitor]]

[[Category: Kinase]]

[[Category: Transferase-transferase inhibitor complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the kinase domain of human PAK1 in complex with compound 15==
+<StructureSection load='4p90' size='340' side='right' caption='[[4p90]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
-The entry 4p90 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4p90]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P90 FirstGlance]. <br>
-Authors: Ferguson, A.D.
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2K0:[2-CHLORO-5-(HYDROXYMETHYL)PHENYL]{5-[1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}METHANONE'>2K0</scene><br>
+<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-Description: Crystal structure of the kinase domain of human PAK1 in complex with compound 15
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p90 RCSB], [http://www.ebi.ac.uk/pdbsum/4p90 PDBsum]</span></td></tr>
+<table>
+__TOC__
+</StructureSection>
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Ferguson, A D.]]
+[[Category: Inhibitor]]
+[[Category: Kinase]]
+[[Category: Transferase-transferase inhibitor complex]]