4pwy: Difference between revisions
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==Crystal structure of a Calmodulin-lysine N-methyltransferase fragment== | |||
=== | <StructureSection load='4pwy' size='340' side='right' caption='[[4pwy]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | |||
==Disease== | <table><tr><td colspan='2'>[[4pwy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PWY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PWY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMKMT, C2orf34, CLNMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calmodulin-lysine_N-methyltransferase Calmodulin-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.60 2.1.1.60] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pwy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pwy RCSB], [http://www.ebi.ac.uk/pdbsum/4pwy PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome. | [[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Atypical hypotonia - cystinuria syndrome;2p21 microdeletion syndrome without cystinuria;2p21 microdeletion syndrome. | ||
== Function == | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref> | [[http://www.uniprot.org/uniprot/CMKMT_HUMAN CMKMT_HUMAN]] Catalyzes the trimethylation of 'Lys-116' in calmodulin.<ref>PMID:20975703</ref> | ||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
<references | |||
[[Category: Calmodulin-lysine N-methyltransferase]] | [[Category: Calmodulin-lysine N-methyltransferase]] | ||
[[Category: Arrowsmith, C H | [[Category: Human]] | ||
[[Category: Bountra, C | [[Category: Arrowsmith, C H]] | ||
[[Category: Brown, P J | [[Category: Bountra, C]] | ||
[[Category: Edwards, A M | [[Category: Brown, P J]] | ||
[[Category: Hong, B S | [[Category: Edwards, A M]] | ||
[[Category: Li, Y | [[Category: Hong, B S]] | ||
[[Category: | [[Category: Li, Y]] | ||
[[Category: Tempel, W | [[Category: Structural genomic]] | ||
[[Category: Walker, J R | [[Category: Tempel, W]] | ||
[[Category: Walker, J R]] | |||
[[Category: Methyl transferase]] | [[Category: Methyl transferase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 08:43, 5 January 2015
Crystal structure of a Calmodulin-lysine N-methyltransferase fragment
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