Sandbox Reserved 911: Difference between revisions
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==Applications== | ==Applications== | ||
The human nervous system has several types of chemical messengers, including amino acids, lipids, peptide hormones, and [http://en.wikipedia.org/wiki/Monoamine_neurotransmitter monoamines] <ref name="1MT5"/>. FAAH primarily degrades [http://www.chm.bris.ac.uk/motm/anandamide/ananh.htm anandamide] (AEA), a naturally-occurring signaling lipid that functions in the brain. AEA brings pain relief to the body. Inhibiting FAAH would likely sustain AEA signaling, leading to prolonged pain relief and decreased inflammation <ref name="2WAP"/>. | The human nervous system has several types of chemical messengers, including amino acids, lipids, peptide hormones, and [http://en.wikipedia.org/wiki/Monoamine_neurotransmitter monoamines] <ref name="1MT5"/>. FAAH primarily [http://www.scripps.edu/cravatt/images/faah_cartoon.gif degrades] [http://www.chm.bris.ac.uk/motm/anandamide/ananh.htm anandamide] (AEA), a naturally-occurring signaling lipid that functions in the brain. AEA brings pain relief to the body. Inhibiting FAAH would likely sustain AEA signaling, leading to prolonged pain relief and decreased inflammation <ref name="2WAP"/>. | ||
[[Image:AEA image.png|200 px|left|thumb|[http://en.wikipedia.org/wiki/File:Anandamide_skeletal.svg Figure 4: Anandamide]]] | [[Image:AEA image.png|200 px|left|thumb|[http://en.wikipedia.org/wiki/File:Anandamide_skeletal.svg Figure 4: Anandamide]]] | ||
