3bv9: Difference between revisions

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New page: left|200px<br /><applet load="3bv9" size="350" color="white" frame="true" align="right" spinBox="true" caption="3bv9, resolution 1.80Å" /> '''Structure of Thrombi...
 
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[[Image:3bv9.jpg|left|200px]]<br /><applet load="3bv9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3bv9.jpg|left|200px]]
caption="3bv9, resolution 1.80&Aring;" />
 
'''Structure of Thrombin Bound to the Inhibitor FM19'''<br />
{{Structure
|PDB= 3bv9 |SIZE=350|CAPTION= <scene name='initialview01'>3bv9</scene>, resolution 1.80&Aring;
|SITE= <scene name='pdbsite=AC1:Oic+Binding+Site+For+Residue+C+402'>AC1</scene>, <scene name='pdbsite=AC2:4ph+Binding+Site+For+Residue+C+405'>AC2</scene>, <scene name='pdbsite=AC3:Iod+Binding+Site+For+Residue+B+303'>AC3</scene>, <scene name='pdbsite=AC4:Na+Binding+Site+For+Residue+B+307'>AC4</scene>, <scene name='pdbsite=AC5:Nh2+Binding+Site+For+Residue+C+406'>AC5</scene> and <scene name='pdbsite=AC6:Gol+Binding+Site+For+Residue+B+305'>AC6</scene>
|LIGAND= <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE= F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of Thrombin Bound to the Inhibitor FM19'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3BV9 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=IOD:'>IOD</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=NH2:'>NH2</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Known structural/functional Sites: <scene name='pdbsite=AC1:Oic+Binding+Site+For+Residue+C+402'>AC1</scene>, <scene name='pdbsite=AC2:4ph+Binding+Site+For+Residue+C+405'>AC2</scene>, <scene name='pdbsite=AC3:Iod+Binding+Site+For+Residue+B+303'>AC3</scene>, <scene name='pdbsite=AC4:Na+Binding+Site+For+Residue+B+307'>AC4</scene>, <scene name='pdbsite=AC5:Nh2+Binding+Site+For+Residue+C+406'>AC5</scene> and <scene name='pdbsite=AC6:Gol+Binding+Site+For+Residue+B+305'>AC6</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BV9 OCA].  
3BV9 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BV9 OCA].  


==Reference==
==Reference==
Molecular dissection of Na+ binding to thrombin., Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E, J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15152000 15152000]
Molecular dissection of Na+ binding to thrombin., Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E, J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15152000 15152000]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: zymogen]]
[[Category: zymogen]]


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