2pnc: Difference between revisions

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'''Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex with Clonidine'''<br />

2PNC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CU:'>CU</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=CLU:'>CLU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Amine_oxidase_(copper-containing) Amine oxidase (copper-containing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.6 1.4.3.6] Known structural/functional Sites: <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+D+800'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+D+801'>AC2</scene>, <scene name='pdbsite=AC3:Nag+Binding+Site+For+Residue+E+800'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+E+801'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+E+802'>AC5</scene>, <scene name='pdbsite=AC6:Cu+Binding+Site+For+Residue+A+901'>AC6</scene>, <scene name='pdbsite=AC7:Cu+Binding+Site+For+Residue+B+901'>AC7</scene>, <scene name='pdbsite=AC8:Ca+Binding+Site+For+Residue+A+902'>AC8</scene>, <scene name='pdbsite=AC9:Ca+Binding+Site+For+Residue+A+903'>AC9</scene>, <scene name='pdbsite=BC1:Cl+Binding+Site+For+Residue+A+904'>BC1</scene>, <scene name='pdbsite=BC2:Ca+Binding+Site+For+Residue+B+905'>BC2</scene>, <scene name='pdbsite=BC3:Ca+Binding+Site+For+Residue+B+906'>BC3</scene>, <scene name='pdbsite=BC4:Cl+Binding+Site+For+Residue+B+907'>BC4</scene>, <scene name='pdbsite=BC5:Cl+Binding+Site+For+Residue+B+908'>BC5</scene>, <scene name='pdbsite=BC6:Clu+Binding+Site+For+Residue+A+1'>BC6</scene> and <scene name='pdbsite=BC7:Clu+Binding+Site+For+Residue+B+1'>BC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNC OCA].  

Multiple binding sites for substrates and modulators of semicarbazide-sensitive amine oxidases: kinetic consequences., Holt A, Smith DJ, Cendron L, Zanotti G, Rigo A, Di Paolo ML, Mol Pharmacol. 2008 Feb;73(2):525-38. Epub 2007 Nov 7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17989349 17989349]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 5 13:25:34 2008''