2q7h: Difference between revisions

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[[Image:2q7h.gif|left|200px]]<br /><applet load="2q7h" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2q7h.gif|left|200px]]
caption="2q7h, resolution 2.10&Aring;" />
 
'''Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate'''<br />
{{Structure
|PDB= 2q7h |SIZE=350|CAPTION= <scene name='initialview01'>2q7h</scene>, resolution 2.10&Aring;
|SITE= <scene name='pdbsite=AC1:Edo+Binding+Site+For+Residue+A+902'>AC1</scene>, <scene name='pdbsite=AC2:Edo+Binding+Site+For+Residue+A+903'>AC2</scene>, <scene name='pdbsite=AC3:Edo+Binding+Site+For+Residue+A+904'>AC3</scene>, <scene name='pdbsite=AC4:Edo+Binding+Site+For+Residue+A+905'>AC4</scene>, <scene name='pdbsite=AC5:Edo+Binding+Site+For+Residue+A+906'>AC5</scene>, <scene name='pdbsite=AC6:Edo+Binding+Site+For+Residue+A+907'>AC6</scene>, <scene name='pdbsite=AC7:Edo+Binding+Site+For+Residue+A+908'>AC7</scene>, <scene name='pdbsite=AC8:Edo+Binding+Site+For+Residue+A+909'>AC8</scene>, <scene name='pdbsite=AC9:Edo+Binding+Site+For+Residue+A+910'>AC9</scene>, <scene name='pdbsite=BC1:Edo+Binding+Site+For+Residue+A+911'>BC1</scene>, <scene name='pdbsite=BC2:Yly+Binding+Site+For+Residue+A+900'>BC2</scene> and <scene name='pdbsite=BC3:Pop+Binding+Site+For+Residue+A+901'>BC3</scene>
|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=YLY:(2R)-2-AMINO-6-({[(2S,3R)-3-METHYLPYRROLIDIN-2-YL]CARBONYL}AMINO)HEXANOYL+[(2S,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL+HYDROGEN+(R)-PHOSPHATE'>YLY</scene> and <scene name='pdbligand=POP:PYROPHOSPHATE 2-'>POP</scene>
|ACTIVITY=
|GENE= pylS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 Methanosarcina mazei])
}}
 
'''Pyrrolysyl-tRNA synthetase bound to adenylated pyrrolysine and pyrophosphate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2Q7H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei] with <scene name='pdbligand=EDO:'>EDO</scene>, <scene name='pdbligand=YLY:'>YLY</scene> and <scene name='pdbligand=POP:'>POP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Edo+Binding+Site+For+Residue+A+902'>AC1</scene>, <scene name='pdbsite=AC2:Edo+Binding+Site+For+Residue+A+903'>AC2</scene>, <scene name='pdbsite=AC3:Edo+Binding+Site+For+Residue+A+904'>AC3</scene>, <scene name='pdbsite=AC4:Edo+Binding+Site+For+Residue+A+905'>AC4</scene>, <scene name='pdbsite=AC5:Edo+Binding+Site+For+Residue+A+906'>AC5</scene>, <scene name='pdbsite=AC6:Edo+Binding+Site+For+Residue+A+907'>AC6</scene>, <scene name='pdbsite=AC7:Edo+Binding+Site+For+Residue+A+908'>AC7</scene>, <scene name='pdbsite=AC8:Edo+Binding+Site+For+Residue+A+909'>AC8</scene>, <scene name='pdbsite=AC9:Edo+Binding+Site+For+Residue+A+910'>AC9</scene>, <scene name='pdbsite=BC1:Edo+Binding+Site+For+Residue+A+911'>BC1</scene>, <scene name='pdbsite=BC2:Yly+Binding+Site+For+Residue+A+900'>BC2</scene> and <scene name='pdbsite=BC3:Pop+Binding+Site+For+Residue+A+901'>BC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q7H OCA].  
2Q7H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q7H OCA].  


==Reference==
==Reference==
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation., Kavran JM, Gundllapalli S, O'Donoghue P, Englert M, Soll D, Steitz TA, Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11268-73. Epub 2007 Jun 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17592110 17592110]
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation., Kavran JM, Gundllapalli S, O'Donoghue P, Englert M, Soll D, Steitz TA, Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11268-73. Epub 2007 Jun 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17592110 17592110]
[[Category: Methanosarcina mazei]]
[[Category: Methanosarcina mazei]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pyrrolysyl-trna synthetase]]
[[Category: pyrrolysyl-trna synthetase]]


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