1t6s: Difference between revisions

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~~{{STRUCTURE_1t6s~~| ~~PDB~~=1t6s | ~~SCENE~~= }}

==Crystal structure of a conserved hypothetical protein from Chlorobium tepidum==

===~~Crystal~~ structure of ~~a conserved hypothetical protein~~ from ~~Chlorobium tepidum~~===

~~{{ABSTRACT_PUBMED_16294331}}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[1t6s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T6S FirstGlance]. <br>

</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>

<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB], [http://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [http://www.topsan.org/Proteins/BSGC/1t6s TOPSAN]</span></td></tr>

<table>

== Evolutionary Conservation ==

[[Image:Consurf_key_small.gif|200px|right]]

Check<jmol>

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t6/1t6s_consurf.spt"</scriptWhenChecked>

<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>

<text>to colour the structure by Evolutionary Conservation</text>

</jmolCheckbox>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

== Publication Abstract from PubMed ==

Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.

~~==Function==~~

Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning.,Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH Proteins. 2006 Feb 1;62(2):322-8. PMID:16294331<ref>PMID:16294331</ref>

~~[[http://www~~.~~uniprot~~.org/uniprot/Q8KF54_CHLTE Q8KF54_CHLTE]] Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (~~By similarity~~).

~~==About this Structure==~~

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

~~[[1t6s]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].~~

</div>

== References ==

==~~Reference~~==

~~<ref group="xtra">PMID:016294331</ref>~~<references ~~group="xtra"~~/><~~references~~/>

__TOC__

</StructureSection>

[[Category: Chlorobium tepidum tls]]

[[Category: BSGC, Berkeley Structural Genomics Center.]]

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-{{STRUCTURE_1t6s|  PDB=1t6s  |  SCENE=  }}
+==Crystal structure of a conserved hypothetical protein from Chlorobium tepidum==
-===Crystal structure of a conserved hypothetical protein from Chlorobium tepidum===
+<StructureSection load='1t6s' size='340' side='right' caption='[[1t6s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-{{ABSTRACT_PUBMED_16294331}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1t6s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T6S FirstGlance]. <br>
+</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene><br>
+<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB], [http://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [http://www.topsan.org/Proteins/BSGC/1t6s TOPSAN]</span></td></tr>
+<table>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t6/1t6s_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.
-==Function==
+Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning.,Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH Proteins. 2006 Feb 1;62(2):322-8. PMID:16294331<ref>PMID:16294331</ref>
-[[http://www.uniprot.org/uniprot/Q8KF54_CHLTE Q8KF54_CHLTE]] Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity).
-==About this Structure==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[1t6s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].
+</div>
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:016294331</ref><references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Chlorobium tepidum tls]]
 [[Category: BSGC, Berkeley Structural Genomics Center.]]