2a5z: Difference between revisions
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==Crystal Structure of Protein of Unknown Function SO2946 from Shewanella oneidensis MR-1== | |||
<StructureSection load='2a5z' size='340' side='right' caption='[[2a5z]], [[Resolution|resolution]] 2.02Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2a5z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sheon Sheon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2A5Z FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SO2946 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211586 SHEON])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a5z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2a5z RCSB], [http://www.ebi.ac.uk/pdbsum/2a5z PDBsum], [http://www.topsan.org/Proteins/MCSG/2a5z TOPSAN]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The crystal structure of the uncharacterized protein SO2946 from Shewanella oneidensis MR-1 was determined with single-wavelength anomalous diffraction (SAD) and refined to 2.0 A resolution. The SO2946 protein consists of a short helical N-terminal domain and a large C-terminal domain with the "jelly-roll" topology. The protein assembles into a propeller consisting of three C-terminal blades arranged around a central core formed by the N-terminal domains. The function of SO2946 could not be inferred from the sequence since the protein represents an orphan with no sequence homologs, but the protein's structure bears a fold similar to that of proteins containing carbohydrate-binding modules. Features such as fold conservation, the presence of a conserved groove and a metal binding region are indicative that SO2946 may be an enzyme and could be involved in binding carbohydrate molecules. | |||
Structure of SO2946 orphan from Shewanella oneidensis shows "jelly-roll" fold with carbohydrate-binding module.,Nocek B, Bigelow L, Abdullah J, Joachimiak A J Struct Funct Genomics. 2008 Dec;9(1-4):1-6. Epub 2008 Jun 20. PMID:18566914<ref>PMID:18566914</ref> | |||
== | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Sheon]] | [[Category: Sheon]] | ||
[[Category: Abdullah, J | [[Category: Abdullah, J]] | ||
[[Category: Bigelow, L | [[Category: Bigelow, L]] | ||
[[Category: Collart, F | [[Category: Collart, F]] | ||
[[Category: Joachimiak, A | [[Category: Joachimiak, A]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Nocek, B | [[Category: Nocek, B]] | ||
[[Category: Hypothetical protein]] | [[Category: Hypothetical protein]] | ||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
[[Category: | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Shewanella oneidensis mr-1]] | [[Category: Shewanella oneidensis mr-1]] | ||
[[Category: So2946]] | [[Category: So2946]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 10:56, 19 November 2014
Crystal Structure of Protein of Unknown Function SO2946 from Shewanella oneidensis MR-1
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