2h54: Difference between revisions

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New page: left|200px<br /><applet load="2h54" size="350" color="white" frame="true" align="right" spinBox="true" caption="2h54, resolution 1.80Å" /> '''Crystal structure of...
 
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[[Image:2h54.jpg|left|200px]]<br /><applet load="2h54" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2h54.jpg|left|200px]]
caption="2h54, resolution 1.80&Aring;" />
 
'''Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)'''<br />
{{Structure
|PDB= 2h54 |SIZE=350|CAPTION= <scene name='initialview01'>2h54</scene>, resolution 1.80&Aring;
|SITE= <scene name='pdbsite=AC1:F3g+Binding+Site+For+Residue+A+501'>AC1</scene>
|LIGAND= <scene name='pdbligand=F3G:3-[2-(2-BENZYLOXYCARBONYLAMINO-3-METHYL-BUTYRYLAMINO)-PROPIONYLAMINO]-4-OXO-PENTANOIC ACID'>F3G</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36]
|GENE= CASP1, IL1BC, IL1BCE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)'''
 


==About this Structure==
==About this Structure==
2H54 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=F3G:'>F3G</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Caspase-1 Caspase-1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.36 3.4.22.36] Known structural/functional Site: <scene name='pdbsite=AC1:F3g+Binding+Site+For+Residue+A+501'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H54 OCA].  
2H54 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H54 OCA].  
[[Category: Caspase-1]]
[[Category: Caspase-1]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:12:50 2008''
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