3bof: Difference between revisions

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'''Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ and Homocysteine'''<br />

3BOF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=YT3:'>YT3</scene> and <scene name='pdbligand=HCS:'>HCS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionine_synthase Methionine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.13 2.1.1.13] Known structural/functional Sites: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+701'>AC1</scene>, <scene name='pdbsite=AC2:Zn+Binding+Site+For+Residue+B+702'>AC2</scene>, <scene name='pdbsite=AC3:K+Binding+Site+For+Residue+A+703'>AC3</scene>, <scene name='pdbsite=AC4:K+Binding+Site+For+Residue+B+704'>AC4</scene>, <scene name='pdbsite=AC5:Yt3+Binding+Site+For+Residue+A+705'>AC5</scene>, <scene name='pdbsite=AC6:Hcs+Binding+Site+For+Residue+A+711'>AC6</scene> and <scene name='pdbsite=AC7:Hcs+Binding+Site+For+Residue+B+712'>AC7</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BOF OCA].  

Metal active site elasticity linked to activation of homocysteine in methionine synthases., Koutmos M, Pejchal R, Bomer TM, Matthews RG, Smith JL, Ludwig ML, Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3286-91. Epub 2008 Feb 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18296644 18296644]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Mar 14 09:38:48 2008''