3buf: Difference between revisions

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New page: left|200px<br /><applet load="3buf" size="350" color="white" frame="true" align="right" spinBox="true" caption="3buf, resolution 2.30Å" /> '''BACE-1 complexed wit...
 
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[[Image:3buf.jpg|left|200px]]<br /><applet load="3buf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3buf.jpg|left|200px]]
caption="3buf, resolution 2.30&Aring;" />
 
'''BACE-1 complexed with compound 2'''<br />
{{Structure
|PDB= 3buf |SIZE=350|CAPTION= <scene name='initialview01'>3buf</scene>, resolution 2.30&Aring;
|SITE= <scene name='pdbsite=AC1:Aeg+Binding+Site+For+Residue+A+394'>AC1</scene>
|LIGAND= <scene name='pdbligand=AEG:'>AEG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46]
|GENE=
}}
 
'''BACE-1 complexed with compound 2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
3BUF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=AEG:'>AEG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] Known structural/functional Site: <scene name='pdbsite=AC1:Aeg+Binding+Site+For+Residue+A+394'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BUF OCA].  
3BUF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BUF OCA].  


==Reference==
==Reference==
Tyramine fragment binding to BACE-1., Kuglstatter A, Stahl M, Peters JU, Huber W, Stihle M, Schlatter D, Benz J, Ruf A, Roth D, Enderle T, Hennig M, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1304-7. Epub 2008 Jan 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18226904 18226904]
Tyramine fragment binding to BACE-1., Kuglstatter A, Stahl M, Peters JU, Huber W, Stihle M, Schlatter D, Benz J, Ruf A, Roth D, Enderle T, Hennig M, Bioorg Med Chem Lett. 2008 Feb 15;18(4):1304-7. Epub 2008 Jan 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18226904 18226904]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: zymogen]]
[[Category: zymogen]]


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