2lfe: Difference between revisions
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<StructureSection load='2lfe' size='340' side='right' caption='[[2lfe]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''> | <StructureSection load='2lfe' size='340' side='right' caption='[[2lfe]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lfe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFE OCA]. <br> | <table><tr><td colspan='2'>[[2lfe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LFE FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HECW2, KIAA1301, NEDL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HECW2, KIAA1301, NEDL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lfe RCSB], [http://www.ebi.ac.uk/pdbsum/2lfe PDBsum]</span></td></tr> | ||
</table> | |||
<table> | == Function == | ||
== | [[http://www.uniprot.org/uniprot/HECW2_HUMAN HECW2_HUMAN]] E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. | ||
==See Also== | |||
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C | [[Category: Arrowsmith, C]] | ||
[[Category: Chitayat, S | [[Category: Chitayat, S]] | ||
[[Category: Dhe-Paganon, S | [[Category: Dhe-Paganon, S]] | ||
[[Category: Garcia, M | [[Category: Garcia, M]] | ||
[[Category: Houliston, S | [[Category: Houliston, S]] | ||
[[Category: Lemak, A | [[Category: Lemak, A]] | ||
[[Category: Montelione, G T | [[Category: Montelione, G T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Yee, A]] | |||
[[Category: Yee, A | |||
[[Category: Ligase]] | [[Category: Ligase]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
Revision as of 17:47, 24 December 2014
Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A
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