GLUT4: Difference between revisions
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New page: <StructureSection load='1suk' size='340' side='right' caption='Glucose Transporter Type 4' scene=''> '''Glucose Transporter Type 4''' (GLUT4) is an insulin-regulated membrane protein respo... |
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<StructureSection load='1suk' size='340' side='right' caption=' | <StructureSection load='1suk' size='340' side='right' caption='Human glucose Transporter Type 4 (PDB code [[1suk]])' scene=''> | ||
'''Glucose Transporter Type 4''' (GLUT4) is an insulin-regulated membrane protein responsible for decreasing blood glucose concentration found in both adipose tissues as well as striated muscle<ref>PMID:17403369</ref>. Activity of this protein is primarily regulated by the signal transduction pathway and several transcriptional factors found in the tissues where GLUT4 is located<ref>PMID:17487684</ref><ref>PMID:11994746</ref><ref>PMID:19448718</ref>. GLUT4 is responsible for returning blood glucose to a physiological concentration of 5-6mM after the ingestion of carbohydrates, as well as increasing the rate of glycogen synthesis in skeletal muscle following glycogen depleting exercise<ref>PMID:15822579</ref><ref>PMID:1699426</ref>. | '''Glucose Transporter Type 4''' (GLUT4) is an insulin-regulated membrane protein responsible for decreasing blood glucose concentration found in both adipose tissues as well as striated muscle<ref>PMID:17403369</ref>. Activity of this protein is primarily regulated by the signal transduction pathway and several transcriptional factors found in the tissues where GLUT4 is located<ref>PMID:17487684</ref><ref>PMID:11994746</ref><ref>PMID:19448718</ref>. GLUT4 is responsible for returning blood glucose to a physiological concentration of 5-6mM after the ingestion of carbohydrates, as well as increasing the rate of glycogen synthesis in skeletal muscle following glycogen depleting exercise<ref>PMID:15822579</ref><ref>PMID:1699426</ref>. | ||
[[Image:Glut4_3d_structure.gif]] | [[Image:Glut4_3d_structure.gif]] | ||
