2mm3: Difference between revisions
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<StructureSection load='2mm3' size='340' side='right' caption='[[2mm3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | <StructureSection load='2mm3' size='340' side='right' caption='[[2mm3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2mm3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MM3 OCA]. <br> | <table><tr><td colspan='2'>[[2mm3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MM3 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHO:GLYCOCHENODEOXYCHOLIC+ACID'>CHO</scene>, <scene name='pdbligand=GCH:GLYCOCHOLIC+ACID'>GCH</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHO:GLYCOCHENODEOXYCHOLIC+ACID'>CHO</scene>, <scene name='pdbligand=GCH:GLYCOCHOLIC+ACID'>GCH</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mm3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mm3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mm3 PDBsum]</span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mm3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mm3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mm3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mm3 PDBsum]</span></td></tr> | </table> | ||
<table> | == Function == | ||
[[http://www.uniprot.org/uniprot/FABP6_HUMAN FABP6_HUMAN]] Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.<ref>PMID:17909007</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Determinants of cooperativity and site selectivity in human ileal bile acid binding protein.,Toke O, Monsey JD, DeKoster GT, Tochtrop GP, Tang C, Cistola DP Biochemistry. 2006 Jan 24;45(3):727-37. PMID:16411748<ref>PMID:16411748</ref> | Determinants of cooperativity and site selectivity in human ileal bile acid binding protein.,Toke O, Monsey JD, DeKoster GT, Tochtrop GP, Tang C, Cistola DP Biochemistry. 2006 Jan 24;45(3):727-37. PMID:16411748<ref>PMID:16411748</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bencsura, A | [[Category: Bencsura, A]] | ||
[[Category: Cistola, D P | [[Category: Cistola, D P]] | ||
[[Category: Covey, D F | [[Category: Covey, D F]] | ||
[[Category: DeKoster, G T | [[Category: DeKoster, G T]] | ||
[[Category: Egyed, O | [[Category: Egyed, O]] | ||
[[Category: Horvath, G | [[Category: Horvath, G]] | ||
[[Category: Simon, A | [[Category: Simon, A]] | ||
[[Category: Tochtrop, G P | [[Category: Tochtrop, G P]] | ||
[[Category: Toke, O | [[Category: Toke, O]] | ||
[[Category: Enterohepatic circulation]] | [[Category: Enterohepatic circulation]] | ||
[[Category: Lipid binding protein]] | [[Category: Lipid binding protein]] | ||
