2wmw: Difference between revisions

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<StructureSection load='2wmw' size='340' side='right' caption='[[2wmw]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
<StructureSection load='2wmw' size='340' side='right' caption='[[2wmw]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WMW OCA]. <br>
<table><tr><td colspan='2'>[[2wmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WMW FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZYW:1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE'>ZYW</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZYW:1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE'>ZYW</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wmt|2wmt]], [[2cgx|2cgx]], [[2c3j|2c3j]], [[2bro|2bro]], [[2brb|2brb]], [[2wmr|2wmr]], [[2wmu|2wmu]], [[2cgv|2cgv]], [[2brh|2brh]], [[2c3k|2c3k]], [[1nvr|1nvr]], [[2wmq|2wmq]], [[1zlt|1zlt]], [[2cgw|2cgw]], [[2brn|2brn]], [[2ayp|2ayp]], [[2wmx|2wmx]], [[1zys|1zys]], [[2cgu|2cgu]], [[1ia8|1ia8]], [[2br1|2br1]], [[2brg|2brg]], [[1nvs|1nvs]], [[2brm|2brm]], [[1nvq|1nvq]], [[2wms|2wms]], [[2wmv|2wmv]], [[2c3l|2c3l]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wmt|2wmt]], [[2cgx|2cgx]], [[2c3j|2c3j]], [[2bro|2bro]], [[2brb|2brb]], [[2wmr|2wmr]], [[2wmu|2wmu]], [[2cgv|2cgv]], [[2brh|2brh]], [[2c3k|2c3k]], [[1nvr|1nvr]], [[2wmq|2wmq]], [[1zlt|1zlt]], [[2cgw|2cgw]], [[2brn|2brn]], [[2ayp|2ayp]], [[2wmx|2wmx]], [[1zys|1zys]], [[2cgu|2cgu]], [[1ia8|1ia8]], [[2br1|2br1]], [[2brg|2brg]], [[1nvs|1nvs]], [[2brm|2brm]], [[1nvq|1nvq]], [[2wms|2wms]], [[2wmv|2wmv]], [[2c3l|2c3l]]</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wmw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wmw RCSB], [http://www.ebi.ac.uk/pdbsum/2wmw PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wmw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wmw RCSB], [http://www.ebi.ac.uk/pdbsum/2wmw PDBsum]</span></td></tr>
<table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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Identification of inhibitors of checkpoint kinase 1 through template screening.,Matthews TP, Klair S, Burns S, Boxall K, Cherry M, Fisher M, Westwood IM, Walton MI, McHardy T, Cheung KM, Van Montfort R, Williams D, Aherne GW, Garrett MD, Reader J, Collins I J Med Chem. 2009 Aug 13;52(15):4810-9. PMID:19572549<ref>PMID:19572549</ref>
Identification of inhibitors of checkpoint kinase 1 through template screening.,Matthews TP, Klair S, Burns S, Boxall K, Cherry M, Fisher M, Westwood IM, Walton MI, McHardy T, Cheung KM, Van Montfort R, Williams D, Aherne GW, Garrett MD, Reader J, Collins I J Med Chem. 2009 Aug 13;52(15):4810-9. PMID:19572549<ref>PMID:19572549</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
== References ==
== References ==
<references/>
<references/>
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