4cpl: Difference between revisions

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<StructureSection load='4cpl' size='340' side='right' caption='[[4cpl]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4cpl' size='340' side='right' caption='[[4cpl]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4cpl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_b_virus_(b/brisbane/60/2008) Influenza b virus (b/brisbane/60/2008)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CPL OCA]. <br>
<table><tr><td colspan='2'>[[4cpl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_b_virus_(b/brisbane/60/2008) Influenza b virus (b/brisbane/60/2008)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CPL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CPL FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cpm|4cpm]], [[4cpn|4cpn]], [[4cpo|4cpo]], [[4cpy|4cpy]], [[4cpz|4cpz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cpm|4cpm]], [[4cpn|4cpn]], [[4cpo|4cpo]], [[4cpy|4cpy]], [[4cpz|4cpz]]</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cpl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cpl RCSB], [http://www.ebi.ac.uk/pdbsum/4cpl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cpl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cpl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cpl RCSB], [http://www.ebi.ac.uk/pdbsum/4cpl PDBsum]</span></td></tr>
<table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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A novel I221 L substitution in neuraminidase confers high level resistance to oseltamivir in influenza B viruses.,Escuret V, Collins PJ, Casalegno JS, Vachieri SG, Cattle N, Ferraris O, Sabatier M, Frobert E, Caro V, Skehel JJ, Gamblin S, Valla F, Valette M, Ottmann M, McCauley JW, Daniels RS, Lina B J Infect Dis. 2014 May 3. PMID:24795482<ref>PMID:24795482</ref>
A novel I221 L substitution in neuraminidase confers high level resistance to oseltamivir in influenza B viruses.,Escuret V, Collins PJ, Casalegno JS, Vachieri SG, Cattle N, Ferraris O, Sabatier M, Frobert E, Caro V, Skehel JJ, Gamblin S, Valla F, Valette M, Ottmann M, McCauley JW, Daniels RS, Lina B J Infect Dis. 2014 May 3. PMID:24795482<ref>PMID:24795482</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
== References ==
== References ==