2xwl: Difference between revisions

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<StructureSection load='2xwl' size='340' side='right' caption='[[2xwl]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
<StructureSection load='2xwl' size='340' side='right' caption='[[2xwl]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XWL OCA]. <br>
<table><tr><td colspan='2'>[[2xwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XWL FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CTP:CYTIDINE-5-TRIPHOSPHATE'>CTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xwn|2xwn]], [[2xwm|2xwm]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xwn|2xwn]], [[2xwm|2xwm]]</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_4-phosphate_cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.60 2.7.7.60] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xwl RCSB], [http://www.ebi.ac.uk/pdbsum/2xwl PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xwl RCSB], [http://www.ebi.ac.uk/pdbsum/2xwl PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/A0R560_MYCS2 A0R560_MYCS2]] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity).[SAAS:SAAS018294_004_010899][HAMAP-Rule:MF_00108]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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Structural and functional studies of mycobacterial IspD enzymes.,Bjorkelid C, Bergfors T, Henriksson LM, Stern AL, Unge T, Mowbray SL, Jones TA Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):403-14. Epub 2011, Apr 8. PMID:21543842<ref>PMID:21543842</ref>
Structural and functional studies of mycobacterial IspD enzymes.,Bjorkelid C, Bergfors T, Henriksson LM, Stern AL, Unge T, Mowbray SL, Jones TA Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):403-14. Epub 2011, Apr 8. PMID:21543842<ref>PMID:21543842</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
==See Also==
*[[MEP cytidylyltransferase|MEP cytidylyltransferase]]
== References ==
== References ==
<references/>
<references/>
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[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
[[Category: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase]]
[[Category: Mycobacterium smegmatis]]
[[Category: Mycobacterium smegmatis]]
[[Category: Bergfors, T.]]
[[Category: Bergfors, T]]
[[Category: Bjorkelid, C.]]
[[Category: Bjorkelid, C]]
[[Category: Jones, T A.]]
[[Category: Jones, T A]]
[[Category: Unge, T.]]
[[Category: Unge, T]]
[[Category: Mep pathway]]
[[Category: Mep pathway]]
[[Category: Transferase]]
[[Category: Transferase]]